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Soy Protein

22 May 2007

22 May, 2007 Dietary Supplements

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Soy Protein

Soy Protein

Soya been is known to be very rich in proteins and it is considered as an important factor to reduce cholesterol in our bodies. It reduces the bad cholesterol referred to as low density lipoprotein –LDL and other risks of developing a heart problem. Soy protein contains isoflavone and the study has shown that it can improve artery function in stroke patients. Patients with cardiovascular disease can use isoflavone supplement found in soy protein to help in improvement of the way brachial artery (the main artery in the arm) dilates in response to an increase in blood flow a phenomenon known as flow mediated dilation (FMD).

According to the research that was conducted by a group of students from university of Hong Kong, China,they came up with the results that after a patient with cardiovascular disease is administered with isoflavoe supplement, which in this case was soy protein for twelve weeks at a dose of 80mg a day, they greatly improved.(Hung-Fat Tse,2004). Brachial FMD is an indicator of the functioning of the cells that usually line the inner surface of blood vessels and endothelial dysfunction which is implicated in cardiovascular disease.

On the study, the trial was conducted by involving thirty patients taking the isoflavone supplement and forty taking placebo pill. The researchers measured FMD using ultrasound to record the rate at which brachial artery performed as the blood flowed.FMD was defined as the percentage change in the brachial artery diameter between its normal size (baseline) and one minute after the tourniquet's deflation. After twelve weeks of isoflavone or placebo,the results showed that eighty percent of the patients who had an impaired FMD of less than 3.7 % had shown improvement of one per cent in the isoflavone patients compared with the controls.

Eighty per cent of the patients had an impaired FMD of less than 3.7% at the start of the study, but after 12 weeks of isoflavone or placebo, there was an improvement of one per cent in the isoflavone-treated patients compared with the controls. The patients with lower initial FMD were found to respond with absolute increase in FMD. The study therefore explained that isoflavone work by reversing endothelial dysfunction in this group of patients. This kind of treatment is conferred to the group of patients who are at high risk for cardiovascular diseases.

No improvement from isoflavone treatment was found in diabetic patients compared with non-diabetic patients, but there was an improvement of one per cent in patients who were current smokers or who had smoked in the past compared with non- or never smokers. This is because smoking is known to be associated with more severe endothelial dysfunction. The findings clearly indicated that patients with worse baseline endothelial function are more responsive to the treatment. (William, 2007)

The research also showed that isoflavone helps to significantly decrese the level of high sensitivity C reactive protein. This protein increases during systematic inflammation and it is an independent predictor of cardiovascular related events. The treatment alleviates vascular inflammatory stress and it is an important component that mediates the reversal of endothelial dysfunction.

Recent findings have showed that major plasma cholesterol is yet to be sustained in recent publications. In some cases, it has been reported that Vasodilatory effects on the microcirculation with isoflavones or their metabolites may provide opportunities for pharmacological intervention. In the past it has been suggested that soy’s potency may be as a result of high amounts of isoflavones but later it was discovered that these natural compounds have shown to have benefits for menopause symptoms and other hormone related conditions, the research therefore concluded that isoflavones do not lower cholesterol.

Some minor reductions in LDL-cholesterol have been reported and those with a parameter of the elasticity or distensibility of large arteries, is improved by as much as has been reported for estrogens.

As many people well understands that soy protein is an important factor to reduce cholesterol, another study showed that soy protein is not effective in reducing cholesterol levels in the blood. It was found that they had no effect on lowering triglyceride level in the blood or on improving the level of good cholesterol (Frank M, 1999). American Heart Association experts also reported that soy is not very effective against the bad cholesterol. They said that soy should be included in the list of foods; low in cholesterol and saturated fat. It was thought that by consuming 25 grams a day reduces the level of cholesterol and in 1999; the FDA stated that soy reduces the risk of heart disease.

It has been noted that people who consumes diet high in soy protein increases their LDL particle size. Women who had mean soy protein intake of 55 grams a day have a great advantage because their cardiovascular activities increase. This is also evident to men who take 71 gram a day an amount which can be obtained from taking soy-based main course each day. Previous studies showed that people who constantly feed on soy are less likely to develop a heart disease and this can help to explain why sales of soy food in Europe is increase by 30 per cent.

High levels of LDL cholesterol contribute to atherosclerosis; this is the narrowing and hardening of the arteries, a condition that is related to increased chances of heart attack. Effect of the protein in soy on the particle size of LDL - a larger LDL particle size is associated with lower risk of heart disease. They examines the outcome of soy protein diets, either enriched or depleted of soy isoflavones compared to common sources of animal protein, either with added isoflavones or without.(Brett,1998)

Consumption of legumes has generally to be encouraged as a strategy to lower plasma lipids. People who consumes legume as a staple food rarely get coronary diseases as legumes have favorable effects of ingested or infused isoflavones on several parameters of arterial function.

About the Author

The author Linda Miller has academic writing experience of over ten years. She holds a PHD in education from Harvard. She has been assisting students in writing professional academic papers including thesis, dissertations, research papers and term papers. braviaresearchpapers.com